Sapreme Technologies is a privately-owned biotech company which develops a disruptive proprietary technology platform (ENDOSCAPE®) enabling the development of novel treatments including antibody-drug conjugates and oligonucleotide-based drugs.

Sapreme is seeking a


  • 40 hour/week
  • Location: Life Sciences Incubator, Utrecht

Job description
You will join an exciting and innovative working environment and be part of a mission to develop new medicines for cancer and other diseases. You will become part of a small ambitious team which develops a variety of drug prototypes, originating from the ENDOSCAPE  platform, both in-house and in collaboration with a number of academic and industrial partners. You will be responsible for biological characterization of a multitude of bio-conjugates including antibody-drug conjugates and other proprietary medicinal scaffolds according to industry-standard quality systems. You will contribute to internal project meetings and will be under the supervision of the Senior Scientist of Sapreme Technologies.

Tasks and Responsibilities

  • You will execute the R&D plans as planned together with the Senior Scientist
  • You are practically profoundly skilled in biological screening and assay development
  • You are comfortable running multiple projects in parallel
  • You enjoy pro-actively proposing solutions and troubleshooting
  • You are accustomed to work-up and analysis of biological material (tissue, blood) sourced from animals
  • You have some basic knowledge of protein / peptide chemistry (cross-linking / conjugation and labeling)
  • You are accustomed to setting-up quality systems, procedures and work documentation
  • You document results accurately and are focused on output and results
  • You contribute to internal meetings and project meetings with collaborators
  • You are accustomed to adhering to deadlines and accept an occasionally enhanced workload
  • You enjoy working in a multi-disciplinary team
  • You are driven by translation of science into products
  • You preferably contribute to the scientific discussions

Key requirements

  • You have a completed HLO education or equivalent
  • You have at least 3 years of working experience in the biotech/pharma/CRO or other relevant industry
  • You have experience with functional assays such as MTS/MTT, proliferation, apoptosis
  • You have experience in analytics including DNA, RNA, FACS, Western Blot, qRT-PCR, cloning, IHC, IF
  • You are familiar with basic statistical and data analysis software such as Excel, GraphPad Prism, FlowJo etc
  • Excellent proficiency in English
  • You have experience in working with proteins including antibodies
  • You have preferably worked in the oncology field
  • You have preferably worked with bio-conjugates
  • Knowledge of, and/or work experience with, regulatory guidelines for product related assays is preferred

We offer
The job is based on a contract for 40 hour/week and salary will be based on relevant work experience.

Should you meet these requirements and be interested in applying for this job, please send your motivation and resume letter to Ruben Postel at Enquiries: +31 30 760 09 76.

We look forward receiving your application.

No agencies

Keywords: Vacancy, Technician, Analist, Biotechnology, Pharmacie, Laboratoriumonderzoek, Laboratoriumtechniek, Utrecht.