Tumor Immunology

  • fulltime
  • Vacancynumber: 2020/0456
  • Closingdate: August 18th 2020
  • Hbo, Wo
  • Apply online

Job description
The successful applicant for this research technician position in tumor immunology will be part of the team that directly contributes to a phase I clinical study testing the safety and feasibility of engineerd T cell therapy such as TEGs and CAR T cell products. The work involves using viral vector-based techniques to engineer primary T cells in both research and GMP environments, and evaluating patient samples using flow cytometry or qPCR techniques. The isolation and culture of primary human immune and tumor cells are also part of the work, as well as setting up, developing and validating new methods and techniques to produce engineered T cells.

The technician will be part of the ATMP development group supervised by Trudy Straetemans within the larger research group of Jurgen Kuball and Zsolt Sebestyen and is embedded in the Tumor Immunology section of the Center for Translational Immunology. It focuses on the development of immune interventions against cancer using immune cells and their receptors. A unique research pipeline from fundamental to translational and clinical research has been established. A key concept developed in this group is a new generation of engineered immune cells named TEGs (T cells Engineered to express a defined Gamma delta T cell receptor). These are currently being tested in a phase I safety/feasibility clinical study at the University Medical Center Utrecht.

You have a professional level of proficiency in English (written and spoken) and are able to think analytically, and have problem-solving skills and a drive to succeed. While you’re able to work independently, you’re also an effective member of a team and have the social skills essential for ensuring fruitful interactions. Not only are you enthusiastic, flexible and accurate in your work, you’re also keen to join an interdisciplinary and international environment. Training and experienced in working under the GMP quality system is an advantage.

We offer
The salary for this 100% position is a maximum of € 3,184.00 gross per month based on a full-time employment contract (working week of 36 hours). It concerns a temporary employment contract for 1 year with the possibility for extension.

Our terms of employment are in accordance with the Cao University Medical Centers (UMC). We offer, among other things, an end-of-year bonus of 8.3%, holiday allowance, a commuting travel allowance and various training options. View our terms of employment and various extras.

More information
For more substantive information about this vacancy, please contact the contact person, Ms Trudy Straetemans, PhD, assistant professor, telephone number: 0887554306, e-mail:

Apply online

Acquisition for this vacancy is not appreciated.

Keywords: Vacature, Technician, Researcher, Analist, Onderzoeksmedewerker, Laboratoriumonderzoek, Onderzoekersondersteuner, Laboratoriumtechniek, HBO, Master, WO, Utrecht