Scenic Biotech, a company that harnesses genetic modifiers to combat disease, is recruiting two Technicians to strengthen its R&D team

About Scenic Biotech

Scenic Biotech BV (est 2017) is a spin out company from the Netherlands Cancer Institute and Oxford University that aims to unlock ‘genetic off-switches’ for rare genetic diseases and cancer. Scenic Biotech is located in Amsterdam, one of the most vibrant European cities and is consistently ranked among the worlds’ cities with the highest quality of life.

The science behind Scenic focuses on the identification of disease suppressing genes, which until recently have proven problematic to uncover. As highlighted in several recent articles in Nature and Science, Scenic’s propriety technology “Cell-Seq” changes the game. Scenic will apply its target identification platform to systematically screen for genes that suppress processes that go awry in disease. These genes serve as a starting point for drug development programs aimed to rebalance a variety of serious diseases. The first in-house lead program in the immuno-oncology space is the result of this approach and additional programs in other indications, particularly rare diseases with unmet medical need, are in progress.

TECHNICIAN (LAB MANAGER)

The successful candidate will be responsible for the day-to-day smoothly running of the lab. In addition, he/she will provide support on specific drug target discovery and development programs.

Specific responsibilities include

  • Purchasing (consumables, equipment) and contacts with sales reps
  • Ensuring all permits/risk assessment documentation is in order
  • Maintaining and improving the general organization of the lab
  • Maintenance and servicing of equipment
  • Provide active support for the Cell-Seq pipeline
  • Generate mutant cell lines using CRISPR/Cas9

Candidate requirements

  • Highly organized and proactive individual with attention for detail
  • Flexible mindset and excellent social and communication skills
  • Minimally BSc (e.g., “HBO”) education in a relevant bio(medical) discipline
  • >3 years work experience, preferably in industry setting
  • Experience with tissue culture or molecular biology is required

TECHNICIAN II (PROJECT SUPPORT) 

The successful candidate will work as a team member on specific drug target discovery and development program(s). He/she will actively participate in project planning and carry out wet lab experiments largely independently.

Specific responsibilities include

  • Perform drug target validation experiments (e.g., cell biology/biochemistry experiments)
  • Establish high throughput screening assays
  • Generate mutant cell lines using CRISPR/Cas9
  • Set up and perform “Cell-Seq” experiments
  • Generate written and oral reports

Candidate requirements

  • Flexible and highly motivated team player
  • Proven ability to deliver quality work within tight deadlines
  • Minimally HBO (BSc) level of a biomedical education with >5 years of professional wet lab experience in academic or industry environment
  • Broad experience in designing, optimizing and using diverse molecular biology, cell biology and biochemical assays
  • Extensive tissue culture experience
  • Experience with genome editing is an advantage

We offer

  • A stimulating and focused environment
  • The opportunity to be part of an enthusiastic team that together builds a new company from the ground up
  • The possibility to contribute to the development of novel therapeutic products for patients
  • A competitive remuneration package, incl. the possibility to share in the success of the company, depending on education/experience

Application procedure

If one or both of the above profiles raised your interest, please send (or share) a short video (max. 1 minute) explaining what makes you the perfect candidate together with your CV and cover letter to jobs@scenicbiotech.com. Don’t forget to mention which of the positions you are applying for. The application deadline is March 15.

References and further reading

  1. Nieuwenhuis J et al. Vasohibins encode tubulin detyrosinating activity. Science 2017
  2. Mezzadra R et al. Identification of CMTM6 and CMTM4 as PD-L1 protein regulators. Nature 2017
  3. Brockmann M, et al. Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling. Nature 2017

No Agencies

Keywords: Vacancy, Research, Technician, Research Technician, Biomedisch, Cell biology, Biochemistry, Molecular biology, Amsterdam, Noord-Holland